As a biological resource-rich country, Malaysia plays a pivotal role in the negotiation of Nagoya Protocol on Access and Benefit Sharing (ABS) and issues emerging from ABS such as Digital Sequence Information of Genetic Resources (DSI). Malaysia acceded to the Nagoya Protocol in November 2018, following the introduction of the Access to Biological Resources and Benefit Sharing Act 2017. At the national level, an effective ABS law and its regulations are at the final stage of preparation to enable implementation of the ABS regime. Hence, Target 14 pertains to the development and operationalization of a national framework on ABS; capacity building and awareness-raising, and the documentation of traditional knowledge of indigenous and local communities (ILCs).